PhD
PhD Proposals
research works
All CARe PhD promotions
Ikram AYOUB, “Study of specific immune responses to antigens in the older people and patients suffering from neuroinflammatory diseases”, Infinity, Team 4: Inflammatory Diseases of the Central Nervous System: Mechanisms and Therapies, Thesis supervisors: Roland Liblau (Infinity), Abdelhadi Saoudi (Infinity)
Emmanuel GONZALEZ BAUTISTA, “Measuring intrinsic capacity in the context of integrated care for the older people”, CERPOP, Team MAINTAIN – MAintain Functions and INTrinsec capacities with Aging: Preventive and Personalized INterventional Research, Thesis supervisors: Sandrine Andrieu (CERPOP), Philipe de Souto Barreto
Julien NOVARINO, “Heterogeneity of follicular CD4 + T lymphocytes controlling B responses”, Infinity, Team 11 : Antigen presenting cells in T Cell Responses, Thesis supervisors: Nicolas Fazilleau (Infinity), Sylvie Guerder
Mathieu VIRAZELS, “Role of TNF-alpha and sphingolipids in the response of melanoma to ‘immune checkpoint’ inhibitors”, CRCT, Team 4: Ceramide metabolism in melanoma: from basic mechanisms to immunotherapy, Thesis supervisors: Bruno Ségui (CRCT), Céline Colacios (CRCT)
Elissa ANDRAOS, “Deciphering the link between resistance and intratumoral heterogeneity in anaplastic large cell lymphoma expressing the oncogenic tyrosine kinase ALK by single-cell transcriptomic analysis and multiparameter phenotyping”, CRCT, Team 7: RNA biology in hematological tumors, Thesis supervisors: Fabienne Meggetto (CRCT), Stéphane Pyronnet (CRCT)
Célia BAK, “Study of epigenetic mechanisms in the aged brain: a new way to prevent cognitive decline”, CRCA, Team: Revealing Memory Mechanisms of the Brain (REMEMBeR), Thesis supervisors: Claire Rampon (CRCA), Cédrick Florian (CRCA)
Clémence BOLUT, “Image processing and calibration”, Restore – Stromalab, Thesis supervisors: Louis Casteilla (Restore), David Simoncini (IRIT)
Camille CHAMPIGNY, “Intrinsic abilities and nutrition in population : the role of Reactive Oxygen Species analyzed by mathematical modelling”, CRCA, Team: Mithochondria, neuronal plasticity and neurodegeneration (MINDING), Thesis supervisors: Noélie Davezac (CRCA), Sophie Guyonnet (Toulouse University Hospital)
Pauline CHASSONERY, “3D models, digital avatar“, Restore, Stromalab, Thesis supervisors: Louis Casteilla (Restore), Diane Peurichard (INRIA)
Luana CINTORI, “Study of the management of targeted oxidative damage to DNA“, CBI, Team Chromatin and cell proliferation, Thesis supervisor: Yvan Canitrot (CBI)
Kévin CORTACERO, “The ontology of lytic synapses: an interdisciplinary approach for the study of cytotoxic T lymphocytes and tumor cell control in the tissues of cancer patients“, CRCT, Team 20: Molecular dynamics of lymphocyte interactions, Thesis supervisors: Salvatore Valitutti (CRCT), Sylvain Cussat-Blanc (IRIT)
Léa DA COSTA FERNANDES, “Modeling of the PROnostic and DIagnosis of Tissue REgeneration in Aging (PRODIRE)”, Restore, Team 1: Plasticity of adipose tissue, Thesis supervisors: Béatrice Cousin (Restore), François Pérès (National School of Engineers of Tarbes)
Ruchan EKREN, “Multimodal investigation of the transcriptomic program of lymphocytes T CD8+ and NK cells in multiple myeloma”, Laboratory: CRCT, Team 13: Genomics and immunology of myeloma, Thesis supervisors, Ludovic Martinet (CRCT), Vera Pancaldi (CRCT)
Mélanie ESCUDERO “Microfabrication of a 3D microphysiological vascularized brown like adipose tissue to treat metabolic and age related dysfunctions”, Restore, Stromalab, Thesis supervisors: Louis Casteilla (Restore), Laurent Malaquin (LAAS)
Matthieu GENAIS, “Prediction of clinical response to immunotherapy in patients with advanced melanoma: a machine learning approach using multi-omics”, CRCT, Team 4: Ceramide metabolism in melanoma: from basic mechanisms to immunotherapy, Thesis supervisors: Bruno Ségui (CRCT), Vera Pancaldi (CRCT)
Wan-Hsuan LU, “Epidemiological approach to intrinsic capacity and inflammation”, CERPOP, MAINTAIN Team, Thesis supervisor: Philipe de Souto Barreto
Laurène Mazeyrie, “Role of the myelomonocytic lineage in Noonan syndrome-associated clinical traits”, I2MC, Team 3: Adipocyte secretions, obesities and related diseases, Thesis supervisors: Armelle Yart (Restore), Thomas Edouard
Snigdha Nitin RAO, “Targeting immunosenescence to prevent kidney disease in elderly patients“, I2MC, Team 12: Renal fibrosis: mechanism and detection, Thesis supervisors: Joost Schanstra (I2MC), Julie Belliere (I2MC)
Anastasia PACARY, “Mechanisms of tissue stiffness and regeneration / rejuvenation”, Restore, Team 1: Plasticity of adipose tissue, Thesis supervisors: Marielle Ousset (Restore), Jenny Paupert (Restore)
Lucie RAPP, “The mouth and the biological ageing process: bidirectional influences and biological markers“, CERPOP, MAINTAIN Team, Thesis supervisor: Jean-Noël Vergnes (CERPOP)
Jacobo SOLORZANO, “Translation Characterization of stroma from pancreatic cancer, towards a new approach to classification”, CRCT, Team 6: Microenvironment and therapeutic resistance in pancreatic neoplasms, Corinne Bousquet (CRCT), Vera Pancaldi (CRCT)
Marion STEPHAN, “Global Redox Potential : Biomarker of the cellular environment homeostasis”, Restore, Thesis supervisors: Cédric Dray (Restore), Pierre Gros
Sanzhar AITBAY, “Bio-Mechanical stress & Signal integration by PI3Ks for the control of tumour growth”, CRCT, Team SydDYN Integrated cell signaling & PI3Ks, Thesis supervisors: Julie Guillermet-Guibert (CRCT), Morgan Delarue (LAAS)
Saber AMRI, “Control of neuroinflammation with bi-therapeutic agents”, Infinity, Team 5, Thesis supervisors: Rémy Poupot (Infinity), Jérôme Ausseil (Infinity)
Sébastien AUBER, “Deciphering the mechanisms of transcription-coupled DSB at enzymatically-induced and endogenous neuronal DSBs by high throughput genomics”, CBI, Team Chromatin & DNA Repair, Thesis supervisors: Gaëlle Legube (CBI), Raphaël Mourad (CBI). Co-tutorship: Huberchet Institute, Utrecht, Netherlands
Silia AYADI, “Identification and characterization of new bioactive lipids”, CRCT, Team INOV, Cholesterol Metabolism and Therapeutic Innovations, Thesis supervisor: Marc Poirot (CRCT)
Mohammed Hussein BAZ, “Laboratory-on-a-chip for the separation of adipose stem cells”, LAAS, Thesis supervisors: Anne-Marie Gué (LAAS), Coralie Sengenes (Restore)
Chloé BRODEAU, “Human skin fibroblasts as indicators of physiological age and frailty”, Restore, Metabolink, Thesis supervisors: Louis Casteilla (Restore), Isabelle Ader (Restore)
Garance CASTINO, “The mitochondrial metabolism of satellite cells: its influence on post-exercise muscular regeneration in aged subjects”, Restore, Metabolink, Thesis supervisors: Cédric Dray (Restore), Philipe de Souto Barreto
Chiara CECCHIN, “Stroma, immunity and metabolism as key understanding of periodontal potential loss with ageing”, Restore, GOT-IT, Thesis supervisors: Philippe Kemoun (Restore), Valérie Planat (Restore)
Maria CHAOUKI, “Treg evolution in B cell lymphoma patients under PI3Kδ inhibition”, CRCT, SigDYN Integrated signalling & PI3K, Thesis supervisors: Julie Guillermet-Guibert (CRCT), Loïc Ysebaert (CRCT)
Lucas CHARPIN, “Laboratory-on-a-chip for the separation of adipose stem cells”, LAAS, Thesis supervisors: Anne-Marie Gué (LAAS), Emmanuelle Trévisiol (TBI)
Emmanuel DOUMARD, “How to explore physiological ageing? A new framework for an in-depth explainability of machine learning models”, IRIT, SIG Team, Thesis supervisors: Chantal Soulé-Dupuy (IRIT), Paul Monsarrat (Restore)
Emma GRANDGIRARD, “Investigating the stroma heterogeneity of adipose tissue using AI-based label free imaging : a predictive marker of frailty ?”, Restore, Stromagics, Thesis supervisors: Coralie Sengenes (Restore), Mathieu Serrurier (IRT Saint-Exupéry, ANITI Team / DEEL)
Alexis HUCTEAU, “In silico, epigenomic and functional investigations of resistance to IDH inhibitors in acute myeloid leukemia”, CRCT, MetAML, Thesis directors: Jean-Emmanuel Sarry (CRCT), Vera Pancaldi (CRCT)
Nikolaos KONTOPOULOS, “Molecular basis of oncolytic virus tropism in pancreatic cancer”, CRCT, Thesis directors: Pierre Cordelier (CRCT), Louis Buscail (CRCT)
Laura LAUTURE, “In vivo study of Gilteritinib resistance in acute myeloid leukemia”, CRCT, MetAML, Thesis director: Jean-Emmanuel Sarry (CRCT)
Léa MAGNE, “Modeling tissue architecture in colorectal physio(patho)logy by image analysis”, IRSD – Inserm, ICA – CNRS, Thesis directors: Audrey Ferrand (IRSD), Florian Bugarin (ICA)
Lisa MARY, “Multi-OMICs to unveil the role of lipid metabolism in the control of senescence and cellular plasticity in melanoma”, CRCT, Melasphinx, Thesis director: Nathalie Andrieu (CRCT)
Rémy MONTANE, “Impact of adipose tissue on systemic redox homeostasis during ageing”, Restore, Metabolink, Thesis directors: Audrey Carrière (Restore) Isabelle Ader (Restore)
Margaux OBERLING, “Investigating the role of alternative splicing in metabolic flexibility and chemotherapy resistance in acute myeloid leukemia”, CRCT, METAML, Thesis director: Margherita Grisi (CRCT)
Gonçalo POMPBA DE ALMEIDA, “Systemic redistribution of metabolic flux by chemotherapy in acute myeloid leukemia”, CRCT, Metabolink, Thesis directors: Jean-Charles Portais (CRCT), Jean-Emmanuel Sarry (CRCT)
Elise PONTHIER, “Development of microphysiological systems by 3D printing for the study of stem cells and the modeling of intestinal tumorigenesis”, CBI, LAAS, Thesis directors: Arnaud Besson (CBI), Laurent Malaquin (LAAS)
Célia RAMADE, “Analysis of T cell responses by omics approaches to understand the mechanisms of resistance to immunotherapy in bronchial and urothelial cancers”, CRCT, T2i Team, Thesis director: Maha Ayyoub (CRCT)
Ophélie THOMAS-CHEMIN, “AutoBioTip: automation of mechanobiological measurements by AFM”, LAAS, Elia, Thesis directors: Etienne Dague (LAAS), Emmanuelle Trévisiol (LAAS)
Haomiao WANG, “Multimodal dataset analysis support system for clinical and biological biomarker detection: proof of concept in oral medicine – PREDINSIGHT 4-D”, Restoire, IRIT, Thesis directors: Paul Monsarrat (Restore), Julien Aligon (IRIT)
Karina CANCINO MALDONADO, “Analysis of preneoplastic lesions related to divergent forms of cancer observed in Peru via single cell analysis technology”, CRCT, Thesis supervisors: Stéphane Bertani (IRD), Frédéric Lopez (CRCT), Mirko Zimic (Universidad Peruana Cayetano Heredia – UCPH)
Maylis COMBEAU, “Preclinical Study of Regenerative Brain Implants”, ToNIC, IMRCP, LAAS, ENVT, Thesis Director: Isabelle Loubinoux (ToNIC)
Léa COSTES, “Physical properties underlying gene mobility during transcription activation”, MCD – CBI, LPT, Thesis Director: Kerstin Bystricky, Manoel Manghi (LPT)
Maëlle DELEUZIERE, “Dual inorganic nanoplatform for a better medical imaging (Nano-diag +)”, LCC, CERPOP, ToNIC, Thesis directors: Eric Benoist (SPCMIB), Isabelle Quelven-Bertin (ToNIC)
Lucas FRASSIN, “Skeletal muscle – adipose tissue dialogue and prevention of metabolic alterations related to lifestyle and age”, I2MC, Thesis directors: Claire Laurens (I2MC), Emilie Montastier (I2MC)
Perrine GIUNCHI, “Development of physioxic gradient microdevices to study the role of a bacterium in colorectal cancer”, IRSD, IMFT, Thesis Directors: Jean-Philippe Nougareyde (IRSD), Yohan Davit (IMFT)
Benjamin JUNG, “Inhibiting TNF to potentiate melanoma response to immune checkpoint inhibitors”, IUCT-O, Thesis directors: Nicolas Meyer (IUCT-O), Anne Montfort (IUCT-O)
Margaux LABROSSE, “Effect of aging on the population of “super” – FAPs originating from adipose tissue and involved in muscle regeneration“, Restore, CBI, Yale University, USA, Thesis directors: Xavier Contreras (Restore), Olivier Cuvier (CBI), Rong Fan (Yale University)